Build and Runes
Nautilus loses his AOE cleave on his auto attacks if you pop his shield, so try to take it down as soon as possible.
Nautilus’s Riptide will hit you multiple times if you move away from him, so stay still if you can.
Nautilus’s ultimate will knock-up any targets in its way to its target, so try not to get in the way.
Junglers ganking bot lane supported by Nautilus, avoid the route in his auto attack or ability range, when going for the adc engage.